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Implication of dorsostriatal D3 receptors in motivational processes: a potential target for neuropsychiatric symptoms in Parkinson’s disease

Beyond classical motor symptoms, motivational and affective deficits are frequently observed in Parkinson’s disease (PD), dramatically impairing the quality of life of patients. Using bilateral 6-hydroxydopamine (6-OHDA) lesions of the substantia nigra pars compacta (SNc) in rats, we have been able...

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Detalles Bibliográficos
Autores principales: Favier, Mathieu, Carcenac, Carole, Drui, Guillaume, Vachez, Yvan, Boulet, Sabrina, Savasta, Marc, Carnicella, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278505/
https://www.ncbi.nlm.nih.gov/pubmed/28134302
http://dx.doi.org/10.1038/srep41589