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Implication of dorsostriatal D3 receptors in motivational processes: a potential target for neuropsychiatric symptoms in Parkinson’s disease
Beyond classical motor symptoms, motivational and affective deficits are frequently observed in Parkinson’s disease (PD), dramatically impairing the quality of life of patients. Using bilateral 6-hydroxydopamine (6-OHDA) lesions of the substantia nigra pars compacta (SNc) in rats, we have been able...
Autores principales: | Favier, Mathieu, Carcenac, Carole, Drui, Guillaume, Vachez, Yvan, Boulet, Sabrina, Savasta, Marc, Carnicella, Sebastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278505/ https://www.ncbi.nlm.nih.gov/pubmed/28134302 http://dx.doi.org/10.1038/srep41589 |
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