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IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis

Patients with rheumatoid arthritis (RA) are at higher risk of developing cardiovascular diseases (CVD). Interleukin (IL)-32 has previously been shown to be involved in the pathogenesis of RA and might be linked to the development of atherosclerosis. However, the exact mechanism linking IL-32 to CVD...

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Detalles Bibliográficos
Autores principales: Damen, Michelle S. M. A., Agca, Rabia, Holewijn, Suzanne, de Graaf, Jacqueline, Dos Santos, Jéssica C., van Riel, Piet L., Fransen, Jaap, Coenen, Marieke J. H., Nurmohamed, Mike T., Netea, Mihai G., Dinarello, Charles A., Joosten, Leo A. B., Heinhuis, Bas, Popa, Calin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278556/
https://www.ncbi.nlm.nih.gov/pubmed/28134327
http://dx.doi.org/10.1038/srep41629