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Chrom3D: three-dimensional genome modeling from Hi-C and nuclear lamin-genome contacts
Current three-dimensional (3D) genome modeling platforms are limited by their inability to account for radial placement of loci in the nucleus. We present Chrom3D, a user-friendly whole-genome 3D computational modeling framework that simulates positions of topologically-associated domains (TADs) rel...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278575/ https://www.ncbi.nlm.nih.gov/pubmed/28137286 http://dx.doi.org/10.1186/s13059-016-1146-2 |