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Inhibition of Plasmodium Liver Infection by Ivermectin

Avermectins are powerful endectocides with an established potential to reduce the incidence of vector-borne diseases. Here, we show that several avermectins inhibit the hepatic stage of Plasmodium infection in vitro. Notably, ivermectin potently inhibits liver infection in vivo by impairing parasite...

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Detalles Bibliográficos
Autores principales: Mendes, António M., Albuquerque, Inês S., Machado, Marta, Pissarra, Joana, Meireles, Patrícia, Prudêncio, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278742/
https://www.ncbi.nlm.nih.gov/pubmed/27895022
http://dx.doi.org/10.1128/AAC.02005-16