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Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer’s Disease

Obesity is associated with impaired memory in humans, and obesity induced by high-fat diets leads to cognitive deficits in rodents and in mouse models of Alzheimer’s disease (AD). However, it remains unclear how high-fat diets contribute to memory impairment. Therefore, we tested the effect of a hig...

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Detalles Bibliográficos
Autores principales: Martins, Isaura V.A., Rivers-Auty, Jack, Allan, Stuart M., Lawrence, Catherine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278950/
https://www.ncbi.nlm.nih.gov/pubmed/27802235
http://dx.doi.org/10.3233/JAD-160640