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Mitochondrial Abnormalities and Synaptic Loss Underlie Memory Deficits Seen in Mouse Models of Obesity and Alzheimer’s Disease
Obesity is associated with impaired memory in humans, and obesity induced by high-fat diets leads to cognitive deficits in rodents and in mouse models of Alzheimer’s disease (AD). However, it remains unclear how high-fat diets contribute to memory impairment. Therefore, we tested the effect of a hig...
Autores principales: | Martins, Isaura V.A., Rivers-Auty, Jack, Allan, Stuart M., Lawrence, Catherine B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5278950/ https://www.ncbi.nlm.nih.gov/pubmed/27802235 http://dx.doi.org/10.3233/JAD-160640 |
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