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An Asymmetrically Balanced Organization of Kinases versus Phosphatases across Eukaryotes Determines Their Distinct Impacts

Protein phosphorylation underlies cellular response pathways across eukaryotes and is governed by the opposing actions of phosphorylating kinases and de-phosphorylating phosphatases. While kinases and phosphatases have been extensively studied, their organization and the mechanisms by which they bal...

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Detalles Bibliográficos
Autores principales: Smoly, Ilan, Shemesh, Netta, Ziv-Ukelson, Michal, Ben-Zvi, Anat, Yeger-Lotem, Esti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279721/
https://www.ncbi.nlm.nih.gov/pubmed/28135269
http://dx.doi.org/10.1371/journal.pcbi.1005221