Inhibition of Myeloperoxidase Activity in Cystic Fibrosis Sputum by Peptide Inhibitor of Complement C1 (PIC1)

Myeloperoxidase is the major peroxidase enzyme in neutrophil granules and implicated in contributing to inflammatory lung damage in cystic fibrosis. Free myeloperoxidase is present in cystic fibrosis lung fluid and generates hypochlorous acid. Here we report a new inhibitor of myeloperoxidase activi...

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Detalles Bibliográficos
Autores principales: Hair, Pamela S., Sass, Laura A., Krishna, Neel K., Cunnion, Kenji M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279725/
https://www.ncbi.nlm.nih.gov/pubmed/28135312
http://dx.doi.org/10.1371/journal.pone.0170203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279725/
https://www.ncbi.nlm.nih.gov/pubmed/28135312
http://dx.doi.org/10.1371/journal.pone.0170203

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