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Evaluation of the Protective Efficacy of Poly I:C as an Adjuvant for H9N2 Subtype Avian Influenza Inactivated Vaccine and Its Mechanism of Action in Ducks

Current commercial H9 avian influenza vaccines cannot provide satisfactory protective immunity against antigenic variant influenza viruses in ducks. Poly I:C, when used as an adjuvant, improves humoral and cellular immunity in many animals but has not been tested in ducks. In this study, we investig...

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Detalles Bibliográficos
Autores principales: Zhang, Aiguo, Lai, Hanzhang, Xu, Jiahua, Huang, Wenke, Liu, Yufu, Zhao, Dawei, Chen, Ruiai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279746/
https://www.ncbi.nlm.nih.gov/pubmed/28135294
http://dx.doi.org/10.1371/journal.pone.0170681