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Evaluation of the Protective Efficacy of Poly I:C as an Adjuvant for H9N2 Subtype Avian Influenza Inactivated Vaccine and Its Mechanism of Action in Ducks
Current commercial H9 avian influenza vaccines cannot provide satisfactory protective immunity against antigenic variant influenza viruses in ducks. Poly I:C, when used as an adjuvant, improves humoral and cellular immunity in many animals but has not been tested in ducks. In this study, we investig...
Autores principales: | Zhang, Aiguo, Lai, Hanzhang, Xu, Jiahua, Huang, Wenke, Liu, Yufu, Zhao, Dawei, Chen, Ruiai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279746/ https://www.ncbi.nlm.nih.gov/pubmed/28135294 http://dx.doi.org/10.1371/journal.pone.0170681 |
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