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Causal role of histone acetylations in enhancer function

Enhancers control development and cellular function by spatiotemporal regulation of gene expression. Co-occurrence of acetylation of histone H3 at lysine 27 (H3K27ac) and mono methylation of histone H3 at lysine 4 (H3K4me1) has been widely used for identification of active enhancers. However, increa...

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Detalles Bibliográficos
Autor principal: Pradeepa, Madapura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279748/
https://www.ncbi.nlm.nih.gov/pubmed/27792455
http://dx.doi.org/10.1080/21541264.2016.1253529