Hepatic Effects of Pharmacological Doses of Hydroxy-Cobalamin[c-lactam] in Mice

The vitamin B(12) analog hydroxy-cobalamin[c-lactam] (HCCL) impairs hepatic mitochondrial protein synthesis and function of the electron transport chain in rats. We aimed to establish an in vivo model for mitochondrial dysfunction in mice, which could be used to investigate hepatotoxicity of mitocho...

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Detalles Bibliográficos
Autores principales: Haegler, Patrizia, Grünig, David, Berger, Benjamin, Terracciano, Luigi, Krähenbühl, Stephan, Bouitbir, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279765/
https://www.ncbi.nlm.nih.gov/pubmed/28135329
http://dx.doi.org/10.1371/journal.pone.0171026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279765/
https://www.ncbi.nlm.nih.gov/pubmed/28135329
http://dx.doi.org/10.1371/journal.pone.0171026

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