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The Spleen Is an Ideal Site for Inducing Transplanted Islet Graft Expansion in Mice

Alternative islet transplantation sites have the potential to reduce the marginal number of islets required to ameliorate hyperglycemia in recipients with diabetes. Previously, we reported that T cell leukemia homeobox 1 (Tlx1)(+) stem cells in the spleen effectively regenerated into insulin-produci...

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Detalles Bibliográficos
Autores principales: Itoh, Takeshi, Nishinakamura, Hitomi, Kumano, Kenjiro, Takahashi, Hiroyuki, Kodama, Shohta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279780/
https://www.ncbi.nlm.nih.gov/pubmed/28135283
http://dx.doi.org/10.1371/journal.pone.0170899