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Early BCR-ABL1 Transcript Decline after 1 Month of Tyrosine Kinase Inhibitor Therapy as an Indicator for Treatment Response in Chronic Myeloid Leukemia

In chronic myeloid leukemia (CML), early treatment prediction is important to identify patients with inferior overall outcomes. We examined the feasibility of using reductions in BCR-ABL1 transcript levels after 1 month of tyrosine kinase inhibitor (TKI) treatment to predict therapy response. Fifty-...

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Detalles Bibliográficos
Autores principales: El Missiry, Mohamed, Hjorth-Hansen, Henrik, Richter, Johan, Olson-Strömberg, Ulla, Stenke, Leif, Porkka, Kimmo, Kreutzman, Anna, Mustjoki, Satu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279791/
https://www.ncbi.nlm.nih.gov/pubmed/28135325
http://dx.doi.org/10.1371/journal.pone.0171041