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Inhibition of a NF-κB/Diap1 Pathway by PGRP-LF Is Required for Proper Apoptosis during Drosophila Development

NF-κB pathways are key signaling cascades of the Drosophila innate immune response. One of them, the Immune Deficiency (IMD) pathway, is under a very tight negative control. Although molecular brakes exist at each step of this signaling module from ligand availability to transcriptional regulation,...

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Detalles Bibliográficos
Autores principales: Tavignot, Raphael, Chaduli, Delphine, Djitte, Fatoumata, Charroux, Bernard, Royet, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279808/
https://www.ncbi.nlm.nih.gov/pubmed/28085885
http://dx.doi.org/10.1371/journal.pgen.1006569