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Effective BRAF inhibitor vemurafenib therapy in a 2-year-old patient with sequentially diagnosed Langerhans cell histiocytosis and Erdheim–Chester disease

Erdheim–Chester disease (ECD) is a rare histiocytic disorder, characterized by the xanthomatous infiltration of tissues by CD68-positive and CD1a-/CD100-negative foamy histiocytes. In childhood, ECD is exceptionally rare, and only a dozen cases have been published so far. The cooccurence of Langerha...

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Detalles Bibliográficos
Autores principales: Váradi, Zsófia, Bánusz, Rita, Csomor, Judit, Kállay, Krisztián, Varga, Edit, Kertész, Gabriella, Csóka, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279823/
https://www.ncbi.nlm.nih.gov/pubmed/28182116
http://dx.doi.org/10.2147/OTT.S121615