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Differential pharmacology and clinical utility of sonidegib in advanced basal cell carcinoma

Patients suffering from advanced basal cell carcinoma (BCC) have very limited treatment options. Sonidegib selectively inhibits the growth of Hedgehog pathway-dependent tumors and can treat locally advanced BCC patients who are not candidates for surgery or radiation therapy. The BOLT clinical trial...

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Detalles Bibliográficos
Autores principales: Wahid, Mohd, Jawed, Arshad, Dar, Sajad Ahmad, Mandal, Raju K, Haque, Shafiul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279825/
https://www.ncbi.nlm.nih.gov/pubmed/28182134
http://dx.doi.org/10.2147/OTT.S97713