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The role of surface charge in the desolvation process of gelatin: implications in nanoparticle synthesis and modulation of drug release
The process of moving hydrophobic amino acids into the core of a protein by desolvation is important in protein folding. However, a rapid and forced desolvation can lead to precipitation of proteins. Desolvation of proteins under controlled conditions generates nanoparticles – homogeneous aggregates...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279841/ https://www.ncbi.nlm.nih.gov/pubmed/28182126 http://dx.doi.org/10.2147/IJN.S124938 |