Blocking iNOS and endoplasmic reticulum stress synergistically improves insulin resistance in mice

OBJECTIVE: Recent data show that iNOS has an essential role in ER stress in obesity. However, whether iNOS is sufficient to account for obesity-induced ER stress and Unfolded Protein Response (UPR) has not yet been investigated. In the present study, we used iNOS knockout mice to investigate whether...

Descripción completa

Detalles Bibliográficos
Autores principales: Zanotto, Tamires M., Quaresma, Paula G.F., Guadagnini, Dioze, Weissmann, Lais, Santos, Andressa C., Vecina, Juliana F., Calisto, Kelly, Santos, Andrey, Prada, Patrícia O., Saad, Mario J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279911/
https://www.ncbi.nlm.nih.gov/pubmed/28180062
http://dx.doi.org/10.1016/j.molmet.2016.12.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279911/
https://www.ncbi.nlm.nih.gov/pubmed/28180062
http://dx.doi.org/10.1016/j.molmet.2016.12.005

Ejemplares similares