Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis

OBJECTIVE: Kinase Suppressor of Ras 2 (KSR2) is a molecular scaffold coordinating Raf/MEK/ERK signaling that is expressed at high levels in the brain. KSR2 disruption in humans and mice causes obesity and insulin resistance. Understanding the anatomical location and mechanism of KSR2 function should...

Descripción completa

Detalles Bibliográficos
Autores principales: Guo, Lili, Costanzo-Garvey, Diane L., Smith, Deandra R., Neilsen, Beth K., MacDonald, Richard G., Lewis, Robert E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279912/
https://www.ncbi.nlm.nih.gov/pubmed/28180061
http://dx.doi.org/10.1016/j.molmet.2016.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279912/
https://www.ncbi.nlm.nih.gov/pubmed/28180061
http://dx.doi.org/10.1016/j.molmet.2016.12.004

Ejemplares similares