Cargando…
Kinase Suppressor of Ras 2 (KSR2) expression in the brain regulates energy balance and glucose homeostasis
OBJECTIVE: Kinase Suppressor of Ras 2 (KSR2) is a molecular scaffold coordinating Raf/MEK/ERK signaling that is expressed at high levels in the brain. KSR2 disruption in humans and mice causes obesity and insulin resistance. Understanding the anatomical location and mechanism of KSR2 function should...
Autores principales: | Guo, Lili, Costanzo-Garvey, Diane L., Smith, Deandra R., Neilsen, Beth K., MacDonald, Richard G., Lewis, Robert E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279912/ https://www.ncbi.nlm.nih.gov/pubmed/28180061 http://dx.doi.org/10.1016/j.molmet.2016.12.004 |
Ejemplares similares
-
Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2)
por: Guo, Lili, et al.
Publicado: (2016) -
Regulation of Glucose Homeostasis by KSR1 and MARK2
por: Klutho, Paula J., et al.
Publicado: (2011) -
Obesity‐dependent dysregulation of glucose homeostasis in kinase suppressor of ras 2(−/−) mice
por: Henry, MaLinda D., et al.
Publicado: (2014) -
Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras
por: Frodyma, Danielle, et al.
Publicado: (2017) -
Kinase Suppressor of RAS 1 (KSR1) Maintains the Transformed Phenotype of BRAFV600E Mutant Human Melanoma Cells
por: Liu, Zhi, et al.
Publicado: (2023)