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Carnitine acetyltransferase (CRAT) expression in macrophages is dispensable for nutrient stress sensing and inflammation

OBJECTIVE: Fatty acid oxidation in macrophages is thought to regulate inflammatory status and insulin-sensitivity. An important unanswered question in this field is whether carnitine acetyl-transferase (CrAT) that regulates fatty acid oxidation and mitochondrial acetyl-CoA balance is required to int...

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Detalles Bibliográficos
Autores principales: Goldberg, Emily L., Dixit, Vishwa Deep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279934/
https://www.ncbi.nlm.nih.gov/pubmed/28180063
http://dx.doi.org/10.1016/j.molmet.2016.12.008