Dipeptidyl peptidase-4 inhibitor treatment induces a greater increase in plasma levels of bioactive GIP than GLP-1 in non-diabetic subjects

OBJECTIVE: Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) possess multiple bioactive isoforms that are rendered non-insulinotropic by the enzyme dipeptidyl peptidase-4 (DPP-4). Recently, some ELISA kits have been developed to specifically measure “active” GIP...

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Detalles Bibliográficos
Autores principales: Yanagimachi, Tsuyoshi, Fujita, Yukihiro, Takeda, Yasutaka, Honjo, Jun, Sakagami, Hidemitsu, Kitsunai, Hiroya, Takiyama, Yumi, Abiko, Atsuko, Makino, Yuichi, Kieffer, Timothy J., Haneda, Masakazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279935/
https://www.ncbi.nlm.nih.gov/pubmed/28180064
http://dx.doi.org/10.1016/j.molmet.2016.12.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279935/
https://www.ncbi.nlm.nih.gov/pubmed/28180064
http://dx.doi.org/10.1016/j.molmet.2016.12.009

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