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Direct measurement of TRPV4 and PIEZO1 activity reveals multiple mechanotransduction pathways in chondrocytes

The joints of mammals are lined with cartilage, comprised of individual chondrocytes embedded in a specialized extracellular matrix. Chondrocytes experience a complex mechanical environment and respond to changing mechanical loads in order to maintain cartilage homeostasis. It has been proposed that...

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Detalles Bibliográficos
Autores principales: Rocio Servin-Vences, M, Moroni, Mirko, Lewin, Gary R, Poole, Kate
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5279942/
https://www.ncbi.nlm.nih.gov/pubmed/28135189
http://dx.doi.org/10.7554/eLife.21074