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IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells
The pathogenic process of intervertebral disc degeneration (IDD) is characterized by imbalance in the extracellular matrix (ECM) metabolism. Nucleus pulposus (NP) cells have important roles in maintaining the proper structure and tissue homeostasis of disc ECM. These cells need adequate supply of gl...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5280875/ https://www.ncbi.nlm.nih.gov/pubmed/28149534 http://dx.doi.org/10.1038/cddiscovery.2016.107 |