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IAPP modulates cellular autophagy, apoptosis, and extracellular matrix metabolism in human intervertebral disc cells

The pathogenic process of intervertebral disc degeneration (IDD) is characterized by imbalance in the extracellular matrix (ECM) metabolism. Nucleus pulposus (NP) cells have important roles in maintaining the proper structure and tissue homeostasis of disc ECM. These cells need adequate supply of gl...

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Detalles Bibliográficos
Autores principales: Wu, Xinghuo, Song, Yu, Liu, Wei, Wang, Kun, Gao, Yong, Li, Shuai, Duan, Zhenfeng, Shao, Zengwu, Yang, Shuhua, Yang, Cao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5280875/
https://www.ncbi.nlm.nih.gov/pubmed/28149534
http://dx.doi.org/10.1038/cddiscovery.2016.107