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Protein Tyrosine Phosphatase 1B (PTP1B): A Potential Target for Alzheimer’s Therapy?

Despite significant advances in current understanding of mechanisms of pathogenesis in Alzheimer’s disease (AD), attempts at drug development based on those discoveries have failed to translate into effective, disease-modifying therapies. AD is a complex and multifactorial disease comprising a range...

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Detalles Bibliográficos
Autores principales: Vieira, Marcelo N. N., Lyra e Silva, Natalia M., Ferreira, Sergio T., De Felice, Fernanda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281585/
https://www.ncbi.nlm.nih.gov/pubmed/28197094
http://dx.doi.org/10.3389/fnagi.2017.00007