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The First Extracellular Linker Is Important for Several Aspects of the Gating Mechanism of Human TRPA1 Channel
Transient receptor potential ankyrin 1 (TRPA1) is an excitatory ion channel involved in pain, inflammation and itching. This channel gates in response to many irritant and proalgesic agents, and can be modulated by calcium and depolarizing voltage. While the closed-state structure of TRPA1 has been...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281607/ https://www.ncbi.nlm.nih.gov/pubmed/28197074 http://dx.doi.org/10.3389/fnmol.2017.00016 |