Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents

The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain tissue but not in Alzheimer’s disease (AD) brain tissue. However, it has not been reported whether the two proteins interact directly, and if so, which domains are involv...

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Detalles Bibliográficos
Autores principales: Canu, Nadia, Pagano, Ilaria, La Rosa, Luca Rosario, Pellegrino, Marsha, Ciotti, Maria Teresa, Mercanti, Delio, Moretti, Fabiola, Sposato, Valentina, Triaca, Viviana, Petrella, Carla, Maruyama, Ichiro N., Levi, Andrea, Calissano, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281621/
https://www.ncbi.nlm.nih.gov/pubmed/28197073
http://dx.doi.org/10.3389/fnmol.2017.00015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281621/
https://www.ncbi.nlm.nih.gov/pubmed/28197073
http://dx.doi.org/10.3389/fnmol.2017.00015

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