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Association of TrkA and APP Is Promoted by NGF and Reduced by Cell Death-Promoting Agents
The amyloid precursor protein (APP) interacts with the tropomyosin receptor kinase A (TrkA) in normal rat, mouse, and human brain tissue but not in Alzheimer’s disease (AD) brain tissue. However, it has not been reported whether the two proteins interact directly, and if so, which domains are involv...
Autores principales: | Canu, Nadia, Pagano, Ilaria, La Rosa, Luca Rosario, Pellegrino, Marsha, Ciotti, Maria Teresa, Mercanti, Delio, Moretti, Fabiola, Sposato, Valentina, Triaca, Viviana, Petrella, Carla, Maruyama, Ichiro N., Levi, Andrea, Calissano, Pietro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281621/ https://www.ncbi.nlm.nih.gov/pubmed/28197073 http://dx.doi.org/10.3389/fnmol.2017.00015 |
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