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SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway

Sirtuin 3 (SIRT3), a mitochondrial protein, is involved in energy metabolism, cell apoptosis and mitochondrial function. However, the role of SIRT3 in neural stem cells (NSCs) remains unknown. In previous studies, we found that microglia activation-induced cytotoxicity negatively regulated survival...

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Detalles Bibliográficos
Autores principales: Jiang, De-Qi, Wang, Yan, Li, Ming-Xing, Ma, Yan-Jiao, Wang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281640/
https://www.ncbi.nlm.nih.gov/pubmed/28197079
http://dx.doi.org/10.3389/fncel.2017.00007