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Elevated regulatory T cells, surface and intracellular CTLA-4 expression and interleukin-17 in the lung cancer microenvironment in humans

Regulatory T cells (Tregs) play an important role in the suppression of the immune response in lung cancer. Cytotoxic T-lymphocyte antigen 4 (CTLA-4) expressed on T lymphocytes is capable of downregulating cytotoxic T cells and is constitutively expressed on Tregs. Little is known about the populati...

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Detalles Bibliográficos
Autores principales: Kwiecien, Iwona, Stelmaszczyk-Emmel, Anna, Polubiec-Kownacka, Malgorzata, Dziedzic, Dariusz, Domagala-Kulawik, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5281670/
https://www.ncbi.nlm.nih.gov/pubmed/27866241
http://dx.doi.org/10.1007/s00262-016-1930-6