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Interface Contractility between Differently Fated Cells Drives Cell Elimination and Cyst Formation

Although cellular tumor-suppression mechanisms are widely studied, little is known about mechanisms that act at the level of tissues to suppress the occurrence of aberrant cells in epithelia. We find that ectopic expression of transcription factors that specify cell fates causes abnormal epithelial...

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Detalles Bibliográficos
Autores principales: Bielmeier, Christina, Alt, Silvanus, Weichselberger, Vanessa, La Fortezza, Marco, Harz, Hartmann, Jülicher, Frank, Salbreux, Guillaume, Classen, Anne-Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282066/
https://www.ncbi.nlm.nih.gov/pubmed/26853359
http://dx.doi.org/10.1016/j.cub.2015.12.063