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The mechanism of formation, structure and physiological relevance of covalent hemoglobin attachment to the erythrocyte membrane
Covalent hemoglobin binding to membranes leads to band 3 (AE1) clustering and the removal of erythrocytes from the circulation; it is also implicated in blood storage lesions. Damaged hemoglobin, with the heme being in a redox and oxygen-binding inactive hemichrome form, has been implicated as the b...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282401/ https://www.ncbi.nlm.nih.gov/pubmed/28007575 http://dx.doi.org/10.1016/j.freeradbiomed.2016.12.024 |