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Cell-SELEX Identifies a “Sticky” RNA Aptamer Sequence

Cell-SELEX is performed to select for cell binding aptamers. We employed an additional selection pressure by using RNAse to remove surface-binding aptamers and select for cell-internalizing aptamers. A common RNA sequence was identified from independent cell-SELEX procedures against two different pa...

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Detalles Bibliográficos
Autores principales: Ray, Partha, White, Rebekah R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282457/
https://www.ncbi.nlm.nih.gov/pubmed/28194280
http://dx.doi.org/10.1155/2017/4943072