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Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration
Endoribonucleases participate in almost every step of eukaryotic RNA metabolism, acting either as degradative or biosynthetic enzymes. We previously identified the founding member of the Eukaryotic EndoU ribonuclease family, whose components display unique biochemical features and are flexibly invol...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282483/ https://www.ncbi.nlm.nih.gov/pubmed/28139767 http://dx.doi.org/10.1038/srep41559 |