Drosophila CG3303 is an essential endoribonuclease linked to TDP-43-mediated neurodegeneration

Endoribonucleases participate in almost every step of eukaryotic RNA metabolism, acting either as degradative or biosynthetic enzymes. We previously identified the founding member of the Eukaryotic EndoU ribonuclease family, whose components display unique biochemical features and are flexibly invol...

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Detalles Bibliográficos
Autores principales: Laneve, Pietro, Piacentini, Lucia, Casale, Assunta Maria, Capauto, Davide, Gioia, Ubaldo, Cappucci, Ugo, Di Carlo, Valerio, Bozzoni, Irene, Di Micco, Patrizio, Morea, Veronica, Di Franco, Carmela Antonia, Caffarelli, Elisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282483/
https://www.ncbi.nlm.nih.gov/pubmed/28139767
http://dx.doi.org/10.1038/srep41559

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