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Non-AUG start codons responsible for ABO weak blood group alleles on initiation mutant backgrounds

Histo-blood group ABO gene polymorphism is crucial in transfusion medicine. We studied the activity and subcellular distribution of ABO gene-encoded A glycosyltransferases with N-terminal truncation. We hypothesized that truncated enzymes starting at internal methionines drove the synthesis of oligo...

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Detalles Bibliográficos
Autores principales: Cid, Emili, Yamamoto, Miyako, Yamamoto, Fumiichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282485/
https://www.ncbi.nlm.nih.gov/pubmed/28139731
http://dx.doi.org/10.1038/srep41720