Cargando…
Non-AUG start codons responsible for ABO weak blood group alleles on initiation mutant backgrounds
Histo-blood group ABO gene polymorphism is crucial in transfusion medicine. We studied the activity and subcellular distribution of ABO gene-encoded A glycosyltransferases with N-terminal truncation. We hypothesized that truncated enzymes starting at internal methionines drove the synthesis of oligo...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282485/ https://www.ncbi.nlm.nih.gov/pubmed/28139731 http://dx.doi.org/10.1038/srep41720 |