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A new model of sperm nuclear architecture following assessment of the organization of centromeres and telomeres in three-dimensions

The organization of chromosomes in sperm nuclei has been proposed to possess a unique “hairpin-loop” arrangement, which is hypothesized to aid in the ordered exodus of the paternal genome following fertilization. This study simultaneously assessed the 3D and 2D radial and longitudinal organization o...

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Detalles Bibliográficos
Autores principales: Ioannou, Dimitrios, Millan, Nicole M., Jordan, Elizabeth, Tempest, Helen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282497/
https://www.ncbi.nlm.nih.gov/pubmed/28139771
http://dx.doi.org/10.1038/srep41585