Roxatidine attenuates mast cell-mediated allergic inflammation via inhibition of NF-κB and p38 MAPK activation

Roxatidine is an active metabolite of roxatidine acetate hydrochloride which is a histamine H(2)-receptor antagonist that is used to treat gastric and duodenal ulcers. In this study, we investigated the anti-allergic inflammatory effects and the underlying molecular mechanism of roxatidine in phorbo...

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Detalles Bibliográficos
Autores principales: Lee, Minho, Lee, Na Young, Chung, Kyung-Sook, Cheon, Se-Yun, Lee, Kyung-Tae, An, Hyo-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282503/
https://www.ncbi.nlm.nih.gov/pubmed/28139747
http://dx.doi.org/10.1038/srep41721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282503/
https://www.ncbi.nlm.nih.gov/pubmed/28139747
http://dx.doi.org/10.1038/srep41721

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