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Inhibition of PDGFR signaling prevents muscular fatty infiltration after rotator cuff tear in mice

Fatty infiltration in muscle is often observed in patients with sizable rotator cuff tear (RCT) and is thought to be an irreversible event that significantly compromises muscle plasticity and contraction strength. These changes in the mechanical properties of the affected muscle render surgical repa...

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Detalles Bibliográficos
Autores principales: Shirasawa, Hideyuki, Matsumura, Noboru, Shimoda, Masayuki, Oki, Satoshi, Yoda, Masaki, Tohmonda, Takahide, Kanai, Yae, Matsumoto, Morio, Nakamura, Masaya, Horiuchi, Keisuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282512/
https://www.ncbi.nlm.nih.gov/pubmed/28139720
http://dx.doi.org/10.1038/srep41552