Young Bone-Marrow Sca-1(+) Stem Cells Rejuvenate the Aged Heart and Improve Function after Injury through PDGFRβ-Akt pathway

Bone marrow (BM) reconstitution with young BM cells in aged recipients restores the functionality of cardiac resident BM-derived progenitors. This study investigated the cell type primarily responsible for this effect. We reconstituted old mice with BM cells from young or old mice and found that the...

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Detalles Bibliográficos
Autores principales: Li, Shu-Hong, Sun, Lu, Yang, Lei, Li, Jiao, Shao, Zhengbo, Du, Guo-Qing, Wu, Jun, Weisel, Richard D., Li, Ren-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282531/
https://www.ncbi.nlm.nih.gov/pubmed/28139736
http://dx.doi.org/10.1038/srep41756

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282531/
https://www.ncbi.nlm.nih.gov/pubmed/28139736
http://dx.doi.org/10.1038/srep41756

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