Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome

Transcriptional variation in histologically- and genetically- identical cells is a widespread phenomenon in tissues, yet the processes conferring this heterogeneity are not well understood. To identify contributing factors, we analyzed epigenetic profiles associated with the in vivo transcriptional...

Descripción completa

Detalles Bibliográficos
Autores principales: Oh, Edward, Jeremian, Richie, Oh, Gabriel, Groot, Daniel, Susic, Miki, Lee, KwangHo, Foy, Kelly, Laird, Peter W., Petronis, Arturas, Labrie, Viviane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282553/
https://www.ncbi.nlm.nih.gov/pubmed/28139744
http://dx.doi.org/10.1038/srep41843

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282553/
https://www.ncbi.nlm.nih.gov/pubmed/28139744
http://dx.doi.org/10.1038/srep41843

Ejemplares similares