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Transcriptional heterogeneity in the lactase gene within cell-type is linked to the epigenome
Transcriptional variation in histologically- and genetically- identical cells is a widespread phenomenon in tissues, yet the processes conferring this heterogeneity are not well understood. To identify contributing factors, we analyzed epigenetic profiles associated with the in vivo transcriptional...
Autores principales: | Oh, Edward, Jeremian, Richie, Oh, Gabriel, Groot, Daniel, Susic, Miki, Lee, KwangHo, Foy, Kelly, Laird, Peter W., Petronis, Arturas, Labrie, Viviane |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282553/ https://www.ncbi.nlm.nih.gov/pubmed/28139744 http://dx.doi.org/10.1038/srep41843 |
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