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A Functional IL22 Polymorphism (rs2227473) Is Associated with Predisposition to Childhood Cerebral Malaria

Cerebral malaria (CM) is a severe complication of Plasmodium falciparum infection. This encephalopathy is characterized by coma and is thought to result from mechanical microvessel obstruction and an excessive activation of immune cells leading to pathological inflammation and blood-brain barrier al...

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Detalles Bibliográficos
Autores principales: Marquet, Sandrine, Conte, Ianina, Poudiougou, Belco, Argiro, Laurent, Dessein, Hélia, Couturier, Charlène, Burté, Florence, Oumar, Aboubacar A., Brown, Biobele J., Traore, Abdoualye, Afolabi, Nathaniel K., Barry, Abdoulaye, Omokhodion, Samuel, Shokunbi, Wuraola A., Sodeinde, Olugbemiro, Doumbo, Ogobara, Fernandez-Reyes, Delmiro, Dessein, Alain J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282577/
https://www.ncbi.nlm.nih.gov/pubmed/28139719
http://dx.doi.org/10.1038/srep41636