Cargando…

Independent movement of the voltage sensors in K(V)2.1/K(V)6.4 heterotetramers

Heterotetramer voltage-gated K(+) (K(V)) channels K(V)2.1/K(V)6.4 display a gating charge-voltage (Q(V)) distribution composed by two separate components. We use state dependent chemical accessibility to cysteines substituted in either K(V)2.1 or K(V)6.4 to assess the voltage sensor movements of eac...

Descripción completa

Detalles Bibliográficos
Autores principales: Bocksteins, Elke, Snyders, Dirk J., Holmgren, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282584/
https://www.ncbi.nlm.nih.gov/pubmed/28139741
http://dx.doi.org/10.1038/srep41646