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Independent movement of the voltage sensors in K(V)2.1/K(V)6.4 heterotetramers
Heterotetramer voltage-gated K(+) (K(V)) channels K(V)2.1/K(V)6.4 display a gating charge-voltage (Q(V)) distribution composed by two separate components. We use state dependent chemical accessibility to cysteines substituted in either K(V)2.1 or K(V)6.4 to assess the voltage sensor movements of eac...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282584/ https://www.ncbi.nlm.nih.gov/pubmed/28139741 http://dx.doi.org/10.1038/srep41646 |