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Germline large genomic alterations on 7q in patients with multiple primary cancers

Patients with multiple primary cancers (MPCs) are suspected to have a hereditary cancer syndrome. However, only a small proportion may be explained by mutations in high-penetrance genes. We investigate two unrelated MPC patients that met Hereditary Breast and Ovaria Cancer criteria, both presenting...

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Detalles Bibliográficos
Autores principales: Villacis, R. A. R., Basso, T. R., Canto, L. M., Nóbrega, A. F., Achatz, M. I., Rogatto, S. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282589/
https://www.ncbi.nlm.nih.gov/pubmed/28139749
http://dx.doi.org/10.1038/srep41677