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Investigation of coordination and order in transcription regulation of innate and adaptive immunity genes in type 1 diabetes

BACKGROUND: Type 1 diabetes (T1D) is an autoimmune disease and extensive evidence has indicated a critical role of both the innate and the adaptive arms of immune system in disease development. To date most clinical trials of immunomodulation therapies failed to show efficacy. A number of gene expre...

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Detalles Bibliográficos
Autores principales: Gao, Shouguo, Wolanyk, Nathaniel, Chen, Ye, Jia, Shuang, Hessner, Martin J., Wang, Xujing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5282641/
https://www.ncbi.nlm.nih.gov/pubmed/28143555
http://dx.doi.org/10.1186/s12920-017-0243-8